CBD has been able to exert several skin biological properties that could be beneficial in various skin pathologies. It showed antitumoral properties in melanoma cells.

CBD has been shown to reduce neuroinflammation and oxidative stress and improve cognitive function and mood. It also has the potential to increase GABAergic transmission in the brain, through agonism at transient receptor potential vanilloid type 1 (TRPV1) and glutamate receptors, and it can help suppress excitatory glutamate neurotransmission in certain areas of the brain, particularly the basal ganglia.

The nervous system is a complex network of nerves that stretches throughout the body, relaying messages from and to the central nervous system and all our organ systems. It’s what makes us move, think, digest, and feel – it’s what makes us who we are.

Effects of CBD on the Immune System

CBD interacts with the endocannabinoid system (ECS) to reduce inflammation. It does this by inhibiting CB2, a receptor that can trigger inflammatory responses. This allows your immune system to respond appropriately for your body to feel better.

CBD drops can also be used to treat autoimmune diseases like MS, where the immune system mistakenly attacks nerve fibres. This causes scar tissue to form, blocking the ability of these fibres to send and receive signals. This causes muscle stiffness and spasticity, which can be reduced by CBD.

While CBD can be effective for some people with autoimmune disorders, it’s important to speak with your doctor before starting any new treatment. Especially if you are taking any other medications, as CBD can interfere with them and may cause side effects. Also, because autoimmune disorders are so poorly understood, traditional treatments have been backed by more research than CBD. However, many people with autoimmune disorders do report that CBD has been helpful for their symptoms.

Effects of CBD on the Cardiovascular System

CBD is known for its positive effects on your heart health. It is a natural plant compound that interacts with the body’s endocannabinoid system (ECS), which manages critical functions such as appetite, mood, sleep, temperature, and reproductive and immune systems.

It has been found that CBD can regulate blood pressure and reduce the risk of cardiovascular disorders such as rheumatoid arthritis and anxiety. It can also lower the risks of heart attacks and strokes by improving your cholesterol levels.

CBD also inhibits sympathetic outflow from the skeletal muscle in the cold pressor test and increases forearm skin blood flow, suggesting that it may have direct cardiovascular actions.

Effects of CBD on the Skin

CBD has been shown to have bactericidal and anti-inflammatory properties, inhibiting cell proliferation, and downregulating the expression of several genes involved in inflammatory processes. When applied topically, CBD has been able to reduce fibrosis in experimental skin fibrosis models and significantly decrease cytokines (IL-4 and IL-6).

In a small study of 11 people with PTSD who took CBD along with their regular medications, researchers found that it reduced their PTSD symptoms. While more research is needed, the findings suggest that CBD may be a promising treatment for inflammatory conditions such as eczema and psoriasis.

Many studies have focused on the topical application of CBD and the development of different semi-solid formulations to enhance its pharmacokinetic, organoleptic, and pharmacological characteristics. Permeation enhancers such as isopropyl myristate, and oleic acid, have been used to improve CBD penetration through the skin. Other enhancement methods such as nanoparticles and emulsions are also being explored to improve skin bioavailability.